Meditation

Meditation Mental training for stress reduction and emotion regulation through meditation practice appears as a promising alternative to improve mental health and well-being in ageing populations and reduce risks for Alzheimer’s disease and other age-related conditions. Our works on meditation include cross-sectional investigations in older expert meditators, and longitudinal non-pharmacological …

Subjective Cognitive Decline

Subjective cognitive decline Why studying SCD in the context of Alzheimer’s disease? One of the main challenges in AD research is to detect the disease as early as possible in order to intervene when the neurodegenerative processes are still limited – and hopefully stoppable or even reversible. The field has …

Hippocampal subfields

Hippocampal subfield Hippocampal atrophy is well-known as an early biomarker of AD, but it lacks specificity as it is also observed in many different situations other than AD such as normal ageing and other neurodegenerative diseases (eg. fronto-temporal dementia, including semantic dementia (SD)). Neuropathological studies have shown that hippocampal subfields …

Lifestyle

Lifestyle The “lifestyle” research line aims at understanding the brain mechanisms underlying the effects of lifestyle factors from normal aging to Alzheimer’s disease dementia. To this aim we use multimodal neuroimaging – amyloid and FDG-PET, structural MRI, resting fMRI and task-related fMRI – and lifestyle assessments -cognitive, physical, social engagement and diet. We are especially interest …