Our Main Studies
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Hippocampal atrophy is well-known as an early biomarker of AD, but it lacks specificity as it is also observed in many different situations other than AD such as normal ageing and other neurodegenerative diseases (eg. fronto-temporal dementia, including semantic dementia (SD)).
The “lifestyle” research group aims at understanding the brain mechanisms underlying the effects of lifestyle factors from normal aging to Alzheimer’s disease dementia.
Multimodal imaging provides a unique opportunity to investigate the temporal and topographical relationship between distinct pathological variables, and thus improve our understanding of pathophysiological interactions in vivo (Teipel et al., 2015).
Subjective Cognitive Decline (SCD)
One of the main challenges in AD research is to detect the disease as early as possible in order to intervene when the neurodegenerative processes are still limited – and hopefully stoppable or even reversible.